BDBM50140679 CHEMBL3752327

SMILES: COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1cccn1

InChI Key: InChIKey=ZOZOUMNWOREEPT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140679 (CHEMBL3752327) Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1cccn1 Show InChI InChI=1S/C21H25N7O3/c1-31-17-6-3-2-5-16(17)26-11-13-27(14-12-26)18-15-19(28-10-4-8-23-28)25-21(24-18)22-9-7-20(29)30/h2-6,8,10,15H,7,9,11-14H2,1H3,(H,29,30)(H,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair