BDBM50140896 CHEMBL3752727::US10383880, Example 14

SMILES: OC(CN(Cc1ccco1)S(=O)(=O)Cc1ccccc1)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=ATBAEWYTYWFVIA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140896 (CHEMBL3752727 | US10383880, Example 14) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)Cc1ccccc1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C27H26N2O4S/c30-22(18-29-26-14-6-4-12-24(26)25-13-5-7-15-27(25)29)17-28(19-23-11-8-16-33-23)34(31,32)20-21-9-2-1-3-10-21/h1-16,22,30H,17-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	652	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140896 (CHEMBL3752727 | US10383880, Example 14) Show SMILES OC(CN(Cc1ccco1)S(=O)(=O)Cc1ccccc1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C27H26N2O4S/c30-22(18-29-26-14-6-4-12-24(26)25-13-5-7-15-27(25)29)17-28(19-23-11-8-16-33-23)34(31,32)20-21-9-2-1-3-10-21/h1-16,22,30H,17-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	415	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair