BDBM50140936 CHEMBL3752183

SMILES: COc1ccc2[nH]c(C)c(\C(=C\c3cccnc3)C#N)c2c1

InChI Key: InChIKey=PZCYBMUUVCANMJ-RIYZIHGNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF20A (Homo sapiens (Human))	BDBM50140936 (CHEMBL3752183) Show SMILES COc1ccc2[nH]c(C)c(\C(=C\c3cccnc3)C#N)c2c1 Show InChI InChI=1S/C18H15N3O/c1-12-18(14(10-19)8-13-4-3-7-20-11-13)16-9-15(22-2)5-6-17(16)21-12/h3-9,11,21H,1-2H3/b14-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr...				Bioorg Med Chem 24: 721-34 (2016) BindingDB Entry DOI: 10.7270/Q29025NR
					More data for this Ligand-Target Pair