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BDBM50141043 CHEMBL39132::N-Ethyloxycarbonyl-3-[4-(2-ethyl-5,7-dimethylimidazo-[4,5-b]pyridin-3-ylmethyl)phenyl]-5-isobutylthiophene-2-sulfonamide

SMILES: CCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1

InChI Key: InChIKey=ZYBJPUVGTLOXES-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141043   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))		BDBM50141043
PNG
(CHEMBL39132 | N-Ethyloxycarbonyl-3-[4-(2-ethyl-5,7...)
Show SMILES CCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Show InChI InChI=1S/C28H34N4O4S2/c1-7-24-30-25-18(5)14-19(6)29-26(25)32(24)16-20-9-11-21(12-10-20)23-15-22(13-17(3)4)37-27(23)38(34,35)31-28(33)36-8-2/h9-12,14-15,17H,7-8,13,16H2,1-6H3,(H,31,33)
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PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement.

J Med Chem 47: 1536-46 (2004)


Article DOI: 10.1021/jm031031i
BindingDB Entry DOI: 10.7270/Q2NS0TBV
More data for this
Ligand-Target Pair