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SMILES: COc1cc(CO)ccc1-c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1

InChI Key: InChIKey=UFAGMYBEPBELPD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141107   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50141107
PNG
(CHEMBL3758351)
Show SMILES COc1cc(CO)ccc1-c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1
Show InChI InChI=1S/C20H15ClFN3O2S/c1-27-17-6-11(9-26)2-4-13(17)18-8-14-19(23-10-24-20(14)28-18)25-12-3-5-16(22)15(21)7-12/h2-8,10,26H,9H2,1H3,(H,23,24,25)
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KEGG

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Similars
PubMed
n/an/a 2n/an/an/an/an/an/a



Norwegian University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) by Z -LYTE assay

Eur J Med Chem 107: 255-74 (2015)


BindingDB Entry DOI: 10.7270/Q2C24Z8D
More data for this
Ligand-Target Pair