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SMILES: COc1ccc(cc1-c1cc2c(N[C@H](C)c3ccccc3)ncnc2s1)C(=O)NCCN(C)C

InChI Key: InChIKey=DXLAGRLIXBCIQY-QGZVFWFLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141108   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50141108
PNG
(CHEMBL3758582)
Show SMILES COc1ccc(cc1-c1cc2c(N[C@H](C)c3ccccc3)ncnc2s1)C(=O)NCCN(C)C |r|
Show InChI InChI=1S/C26H29N5O2S/c1-17(18-8-6-5-7-9-18)30-24-21-15-23(34-26(21)29-16-28-24)20-14-19(10-11-22(20)33-4)25(32)27-12-13-31(2)3/h5-11,14-17H,12-13H2,1-4H3,(H,27,32)(H,28,29,30)/t17-/m1/s1
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Similars
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Norwegian University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) by Z -LYTE assay

Eur J Med Chem 107: 255-74 (2015)


BindingDB Entry DOI: 10.7270/Q2C24Z8D
More data for this
Ligand-Target Pair