BDBM50141538 (E)-3-(2,4-Dimethoxy-5-thiophen-2-yl-phenyl)-1-(2,3,4-trimethoxy-phenyl)-propenone::CHEMBL37382

SMILES: COc1cc(OC)c(cc1\C=C\C(=O)c1ccc(OC)c(OC)c1OC)-c1cccs1

InChI Key: InChIKey=SKROZJJONYEAQS-CSKARUKUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50141538 ((E)-3-(2,4-Dimethoxy-5-thiophen-2-yl-phenyl)-1-(2,...) Show SMILES COc1cc(OC)c(cc1\C=C\C(=O)c1ccc(OC)c(OC)c1OC)-c1cccs1 Show InChI InChI=1S/C24H24O6S/c1-26-19-11-9-16(23(29-4)24(19)30-5)18(25)10-8-15-13-17(22-7-6-12-31-22)21(28-3)14-20(15)27-2/h6-14H,1-5H3/b10-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AtheroGenics, Inc. Curated by ChEMBL					Assay Description Inhibition of TNF-alpha-induced VCAM-1 expression				Bioorg Med Chem Lett 14: 1513-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.021 BindingDB Entry DOI: 10.7270/Q2028QZK
					More data for this Ligand-Target Pair