Found 3 hits for monomerid = 50141572 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prothrombin
(Homo sapiens (Human)) | BDBM50141572
(Azaphenylalanine derivative | CHEMBL41359)Show SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)NN(Cc1cccc(c1)C(=N)NO)C(=O)N1CCCCC1C Show InChI InChI=1S/C26H31N5O5S/c1-18-6-3-4-13-30(18)26(32)31(17-19-7-5-8-22(14-19)25(27)28-33)29-37(34,35)24-12-10-20-15-23(36-2)11-9-21(20)16-24/h5,7-12,14-16,18,29,33H,3-4,6,13,17H2,1-2H3,(H2,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description In vitro inhibition of human alpha-thrombin |
Bioorg Med Chem Lett 14: 1563-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.083 BindingDB Entry DOI: 10.7270/Q2QJ7GQH |
More data for this Ligand-Target Pair | |
Trypsin-1
(Homo sapiens (Human)) | BDBM50141572
(Azaphenylalanine derivative | CHEMBL41359)Show SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)NN(Cc1cccc(c1)C(=N)NO)C(=O)N1CCCCC1C Show InChI InChI=1S/C26H31N5O5S/c1-18-6-3-4-13-30(18)26(32)31(17-19-7-5-8-22(14-19)25(27)28-33)29-37(34,35)24-12-10-20-15-23(36-2)11-9-21(20)16-24/h5,7-12,14-16,18,29,33H,3-4,6,13,17H2,1-2H3,(H2,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description In vitro inhibition of trypsin |
Bioorg Med Chem Lett 14: 1563-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.083 BindingDB Entry DOI: 10.7270/Q2QJ7GQH |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50141572
(Azaphenylalanine derivative | CHEMBL41359)Show SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)NN(Cc1cccc(c1)C(=N)NO)C(=O)N1CCCCC1C Show InChI InChI=1S/C26H31N5O5S/c1-18-6-3-4-13-30(18)26(32)31(17-19-7-5-8-22(14-19)25(27)28-33)29-37(34,35)24-12-10-20-15-23(36-2)11-9-21(20)16-24/h5,7-12,14-16,18,29,33H,3-4,6,13,17H2,1-2H3,(H2,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.11E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description In vitro inhibition of Coagulation factor X |
Bioorg Med Chem Lett 14: 1563-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.083 BindingDB Entry DOI: 10.7270/Q2QJ7GQH |
More data for this Ligand-Target Pair | |