BDBM50141812 2-(2-{4-[4-(4-tert-Butyl-phenylamino)-2-fluoro-phenoxy]-6-methoxy-quinolin-7-yloxy}-ethylamino)-ethanol::CHEMBL354898

SMILES: COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3F)ccnc2cc1OCCNCCO

InChI Key: InChIKey=GLHJMXRTDQUEOS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141812 (2-(2-{4-[4-(4-tert-Butyl-phenylamino)-2-fluoro-phe...) Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3F)ccnc2cc1OCCNCCO Show InChI InChI=1S/C30H34FN3O4/c1-30(2,3)20-5-7-21(8-6-20)34-22-9-10-27(24(31)17-22)38-26-11-12-33-25-19-29(28(36-4)18-23(25)26)37-16-14-32-13-15-35/h5-12,17-19,32,34-35H,13-16H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair