BDBM50141814 CHEMBL276125::[4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenyl]-(4-isopropyl-phenyl)-amine

SMILES: COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)C)cc3)c2cc1OC

InChI Key: InChIKey=ZOZFANGNXJDGKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141814 (CHEMBL276125 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...) Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)C)cc3)c2cc1OC Show InChI InChI=1S/C26H26N2O3/c1-17(2)18-5-7-19(8-6-18)28-20-9-11-21(12-10-20)31-24-13-14-27-23-16-26(30-4)25(29-3)15-22(23)24/h5-17,28H,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair