BDBM50141816 1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-methoxy-quinolin-7-yloxy}-3-piperidin-1-yl-propan-2-ol::CHEMBL169397

SMILES: COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCC(O)CN1CCCCC1

InChI Key: InChIKey=TYILTPXOEDGRFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141816 (1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...) Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCC(O)CN1CCCCC1 Show InChI InChI=1S/C34H41N3O4/c1-34(2,3)24-8-10-25(11-9-24)36-26-12-14-28(15-13-26)41-31-16-17-35-30-21-33(32(39-4)20-29(30)31)40-23-27(38)22-37-18-6-5-7-19-37/h8-17,20-21,27,36,38H,5-7,18-19,22-23H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair