BDBM50141817 CHEMBL171509::[1-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-methoxy-quinolin-7-yloxy}-ethyl)-piperidin-4-yl]-methanol

SMILES: COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCN1CCC(CO)CC1

InChI Key: InChIKey=DZWNRLQHJUUWFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141817 (CHEMBL171509 | [1-(2-{4-[4-(4-tert-Butyl-phenylami...) Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCN1CCC(CO)CC1 Show InChI InChI=1S/C34H41N3O4/c1-34(2,3)25-5-7-26(8-6-25)36-27-9-11-28(12-10-27)41-31-13-16-35-30-22-33(32(39-4)21-29(30)31)40-20-19-37-17-14-24(23-38)15-18-37/h5-13,16,21-22,24,36,38H,14-15,17-20,23H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair