BDBM50141818 Biphenyl-3-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-phenyl]-amine::CHEMBL353884

SMILES: COc1cc2nccc(Oc3ccc(Nc4cccc(c4)-c4ccccc4)cc3)c2cc1OC

InChI Key: InChIKey=VFKPRDPHVLFEKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141818 (Biphenyl-3-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...) Show SMILES COc1cc2nccc(Oc3ccc(Nc4cccc(c4)-c4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H24N2O3/c1-32-28-18-25-26(19-29(28)33-2)30-16-15-27(25)34-24-13-11-22(12-14-24)31-23-10-6-9-21(17-23)20-7-4-3-5-8-20/h3-19,31H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair