BDBM50141820 (4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-trifluoromethyl-phenyl]-amine::CHEMBL171161

SMILES: COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(c3)C(F)(F)F)c2cc1OC

InChI Key: InChIKey=GITYRAHBAJTUGI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141820 ((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...) Show SMILES COc1cc2nccc(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)c(c3)C(F)(F)F)c2cc1OC Show InChI InChI=1S/C28H27F3N2O3/c1-27(2,3)17-6-8-18(9-7-17)33-22-11-10-19(14-21(22)28(29,30)31)36-24-12-13-32-23-16-26(35-5)25(34-4)15-20(23)24/h6-16,33H,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair