BDBM50141826 CHEMBL354830::[4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenyl]-(4-methoxy-phenyl)-amine
SMILES: COc1ccc(Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1
InChI Key: InChIKey=XYMSFXXPWXFMIO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM50141826 (CHEMBL354830 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co., Ltd. Curated by ChEMBL | Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line | Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV | |||||||||||
More data for this Ligand-Target Pair |