BDBM50141830 4-[4-(4-tert-Butyl-benzyl)-phenoxy]-6,7-dimethoxy-quinoline::CHEMBL353668

SMILES: COc1cc2nccc(Oc3ccc(Cc4ccc(cc4)C(C)(C)C)cc3)c2cc1OC

InChI Key: InChIKey=HJVDLBKBEURQDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141830 (4-[4-(4-tert-Butyl-benzyl)-phenoxy]-6,7-dimethoxy-...) Show SMILES COc1cc2nccc(Oc3ccc(Cc4ccc(cc4)C(C)(C)C)cc3)c2cc1OC Show InChI InChI=1S/C28H29NO3/c1-28(2,3)21-10-6-19(7-11-21)16-20-8-12-22(13-9-20)32-25-14-15-29-24-18-27(31-5)26(30-4)17-23(24)25/h6-15,17-18H,16H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair