BDBM50141831 (4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)-quinolin-4-yloxy]-phenyl}-amine::CHEMBL355436

SMILES: COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=KCKZQDGTIBXQNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50141831 ((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(3-piperidin...) Show SMILES COc1cc2c(Oc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C34H41N3O3/c1-34(2,3)25-9-11-26(12-10-25)36-27-13-15-28(16-14-27)40-31-17-18-35-30-24-33(32(38-4)23-29(30)31)39-22-8-21-37-19-6-5-7-20-37/h9-18,23-24,36H,5-8,19-22H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell line				Bioorg Med Chem Lett 14: 875-9 (2004) Article DOI: 10.1016/j.bmcl.2003.12.019 BindingDB Entry DOI: 10.7270/Q2TB16BV
					More data for this Ligand-Target Pair