BDBM50142085 CHEMBL3760100

SMILES: Cc1ccc(cc1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(cc1)C(=O)NC1CC1

InChI Key: InChIKey=WSLNJPSSJUGUCS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142085   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142085 (CHEMBL3760100) Show SMILES Cc1ccc(cc1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(cc1)C(=O)NC1CC1 Show InChI InChI=1S/C28H31N3O2/c1-19-2-4-22(5-3-19)27-26(16-25(17-30-27)33-18-20-12-14-29-15-13-20)21-6-8-23(9-7-21)28(32)31-24-10-11-24/h2-9,16-17,20,24,29H,10-15,18H2,1H3,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair