BDBM50142094 2'-[1,4]Diazepan-1-yl-biphenyl-4-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenyl]-amide::CHEMBL368544

SMILES: Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2ccccc2N2CCCNCC2)nc1

InChI Key: InChIKey=QAOJXMKGOCECEF-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50142094 (2'-[1,4]Diazepan-1-yl-biphenyl-4-carboxylic acid [...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2ccccc2N2CCCNCC2)nc1 Show InChI InChI=1S/C30H27Cl2N5O2/c31-22-10-12-26(25(18-22)30(39)36-28-13-11-23(32)19-34-28)35-29(38)21-8-6-20(7-9-21)24-4-1-2-5-27(24)37-16-3-14-33-15-17-37/h1-2,4-13,18-19,33H,3,14-17H2,(H,35,38)(H,34,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Coagulation factor X				Bioorg Med Chem Lett 14: 983-7 (2004) Article DOI: 10.1016/j.bmcl.2003.11.079 BindingDB Entry DOI: 10.7270/Q21V5DF7
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142094 (2'-[1,4]Diazepan-1-yl-biphenyl-4-carboxylic acid [...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2ccccc2N2CCCNCC2)nc1 Show InChI InChI=1S/C30H27Cl2N5O2/c31-22-10-12-26(25(18-22)30(39)36-28-13-11-23(32)19-34-28)35-29(38)21-8-6-20(7-9-21)24-4-1-2-5-27(24)37-16-3-14-33-15-17-37/h1-2,4-13,18-19,33H,3,14-17H2,(H,35,38)(H,34,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Coagulation factor X				Bioorg Med Chem Lett 14: 983-7 (2004) Article DOI: 10.1016/j.bmcl.2003.11.079 BindingDB Entry DOI: 10.7270/Q21V5DF7
					More data for this Ligand-Target Pair