BindingDB PrimarySearch

BDBM50142142 5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dimethyl-hydrazinomethyl)-benzoylamino]-benzamide::CHEMBL176671

SMILES: CN(C)NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=XPKNJXWMMWULIE-UHFFFAOYSA-N

Data: 1 KI 7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50142142
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against plasmin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against kallikrein				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against tissue type plasminogen activator.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against activated protein C				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against thrombin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against trypsin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair