BDBM50142349 2-{(2R,5R)-2-(2,4-Dichloro-phenyl)-4-oxo-5-[((R)-1-phenyl-ethylcarbamoyl)-methyl]-thiazolidin-3-yl}-N-(3-morpholin-4-yl-propyl)-acetamide::CHEMBL44198

SMILES: C[C@@H](NC(=O)C[C@H]1S[C@@H](N(CC(=O)NCCCN2CCOCC2)C1=O)c1ccc(Cl)cc1Cl)c1ccccc1

InChI Key: InChIKey=ZXXLWKKFCLKYQY-WJPVBLRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50142349 (2-{(2R,5R)-2-(2,4-Dichloro-phenyl)-4-oxo-5-[((R)-1...) Show SMILES C[C@@H](NC(=O)C[C@H]1S[C@@H](N(CC(=O)NCCCN2CCOCC2)C1=O)c1ccc(Cl)cc1Cl)c1ccccc1 Show InChI InChI=1S/C28H34Cl2N4O4S/c1-19(20-6-3-2-4-7-20)32-25(35)17-24-27(37)34(28(39-24)22-9-8-21(29)16-23(22)30)18-26(36)31-10-5-11-33-12-14-38-15-13-33/h2-4,6-9,16,19,24,28H,5,10-15,17-18H2,1H3,(H,31,36)(H,32,35)/t19-,24-,28-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of [125I]-MDC binding to recombinant human C-C chemokine receptor type 4 (CCR4) expressed in murine pre-B cells				Bioorg Med Chem Lett 14: 1619-24 (2004) Article DOI: 10.1016/j.bmcl.2004.01.072 BindingDB Entry DOI: 10.7270/Q2W37VRK
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50142349 (2-{(2R,5R)-2-(2,4-Dichloro-phenyl)-4-oxo-5-[((R)-1...) Show SMILES C[C@@H](NC(=O)C[C@H]1S[C@@H](N(CC(=O)NCCCN2CCOCC2)C1=O)c1ccc(Cl)cc1Cl)c1ccccc1 Show InChI InChI=1S/C28H34Cl2N4O4S/c1-19(20-6-3-2-4-7-20)32-25(35)17-24-27(37)34(28(39-24)22-9-8-21(29)16-23(22)30)18-26(36)31-10-5-11-33-12-14-38-15-13-33/h2-4,6-9,16,19,24,28H,5,10-15,17-18H2,1H3,(H,31,36)(H,32,35)/t19-,24-,28-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of [125I]-MDC binding to recombinant human C-C chemokine receptor type 4 (CCR4) expressed in murine pre-B cells				Bioorg Med Chem Lett 14: 1619-24 (2004) Article DOI: 10.1016/j.bmcl.2004.01.072 BindingDB Entry DOI: 10.7270/Q2W37VRK
					More data for this Ligand-Target Pair