BDBM50142530 3,4,5-Trihydroxy-N-phenyl-benzamide::CHEMBL43782

SMILES: Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1

InChI Key: InChIKey=HLVGXGQCLASQJU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase I (Topo I) (Homo sapiens (Human))	BDBM50142530 (3,4,5-Trihydroxy-N-phenyl-benzamide | CHEMBL43782) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C13H11NO4/c15-10-6-8(7-11(16)12(10)17)13(18)14-9-4-2-1-3-5-9/h1-7,15-17H,(H,14,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair