BDBM50142582 4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-phenylamine::CHEMBL47687

SMILES: COc1ccc(cc1)-n1nc(cc1-c1ccc(N)cc1)C(F)(F)F

InChI Key: InChIKey=LSRVZDWLTQYIEE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50142582 (4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(18,19)20)11-2-4-12(21)5-3-11/h2-10H,21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50142582 (4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(N)cc1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(18,19)20)11-2-4-12(21)5-3-11/h2-10H,21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesicles				Bioorg Med Chem Lett 14: 1683-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.053 BindingDB Entry DOI: 10.7270/Q23N22TF
					More data for this Ligand-Target Pair