null

SMILES: Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)N1CCc2ccccc2C1

InChI Key: InChIKey=RMFGZBFRUYKMOT-URLMMPGGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50142704 (CHEMBL3758563) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)N1CCc2ccccc2C1 |r| Show InChI InChI=1S/C32H36N4O4/c1-20-13-26(37)14-21(2)27(20)16-28(33)32(40)36-19-25-10-6-4-8-23(25)15-29(36)31(39)34-17-30(38)35-12-11-22-7-3-5-9-24(22)18-35/h3-10,13-14,28-29,37H,11-12,15-19,33H2,1-2H3,(H,34,39)/t28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membrane				Eur J Med Chem 108: 211-28 (2016) BindingDB Entry DOI: 10.7270/Q2R2137W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50142704 (CHEMBL3758563) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)N1CCc2ccccc2C1 |r| Show InChI InChI=1S/C32H36N4O4/c1-20-13-26(37)14-21(2)27(20)16-28(33)32(40)36-19-25-10-6-4-8-23(25)15-29(36)31(39)34-17-30(38)35-12-11-22-7-3-5-9-24(22)18-35/h3-10,13-14,28-29,37H,11-12,15-19,33H2,1-2H3,(H,34,39)/t28-,29+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membrane				Eur J Med Chem 108: 211-28 (2016) BindingDB Entry DOI: 10.7270/Q2R2137W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50142704 (CHEMBL3758563) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)N1CCc2ccccc2C1 |r| Show InChI InChI=1S/C32H36N4O4/c1-20-13-26(37)14-21(2)27(20)16-28(33)32(40)36-19-25-10-6-4-8-23(25)15-29(36)31(39)34-17-30(38)35-12-11-22-7-3-5-9-24(22)18-35/h3-10,13-14,28-29,37H,11-12,15-19,33H2,1-2H3,(H,34,39)/t28-,29+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gammaS binding assay				Eur J Med Chem 108: 211-28 (2016) BindingDB Entry DOI: 10.7270/Q2R2137W
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50142704 (CHEMBL3758563) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)N1CCc2ccccc2C1 |r| Show InChI InChI=1S/C32H36N4O4/c1-20-13-26(37)14-21(2)27(20)16-28(33)32(40)36-19-25-10-6-4-8-23(25)15-29(36)31(39)34-17-30(38)35-12-11-22-7-3-5-9-24(22)18-35/h3-10,13-14,28-29,37H,11-12,15-19,33H2,1-2H3,(H,34,39)/t28-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Antagonist activity at human delta opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO-induced [35S]-GTP-gammaS binding				Eur J Med Chem 108: 211-28 (2016) BindingDB Entry DOI: 10.7270/Q2R2137W
					More data for this Ligand-Target Pair