BDBM50143015 CHEMBL3758549

SMILES: Brc1cccc(COc2ccc(CC3SC(=O)NC3=O)cc2)c1

InChI Key: InChIKey=REXWEDIBMQCBQS-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50143015 (CHEMBL3758549) Show SMILES Brc1cccc(COc2ccc(CC3SC(=O)NC3=O)cc2)c1 Show InChI InChI=1S/C17H14BrNO3S/c18-13-3-1-2-12(8-13)10-22-14-6-4-11(5-7-14)9-15-16(20)19-17(21)23-15/h1-8,15H,9-10H2,(H,19,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Transactivation of N-terminal Gal4 DNA binding domain-linked human PPARalpha ligand binding domain after 24 hrs by luciferase reporter gene assay rel...				Eur J Med Chem 109: 157-72 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2JMM
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50143015 (CHEMBL3758549) Show SMILES Brc1cccc(COc2ccc(CC3SC(=O)NC3=O)cc2)c1 Show InChI InChI=1S/C17H14BrNO3S/c18-13-3-1-2-12(8-13)10-22-14-6-4-11(5-7-14)9-15-16(20)19-17(21)23-15/h1-8,15H,9-10H2,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.57E+3	n/a	n/a	n/a	n/a
Suez Canal University Curated by ChEMBL					Assay Description Agonist activity at human FFAR1 expressed in CHO-K1 cells assessed as calcium flux measured for 100 secs by FLIPR assay				Eur J Med Chem 109: 157-72 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2JMM
					More data for this Ligand-Target Pair