BDBM50143085 CHEMBL3759846
SMILES: Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1
InChI Key: InChIKey=UUNCSSVBRBKVQA-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human)) | BDBM50143085 (CHEMBL3759846) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization | Bioorg Med Chem Lett 26: 751-6 (2016) BindingDB Entry DOI: 10.7270/Q261124T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50143085 (CHEMBL3759846) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization | Bioorg Med Chem Lett 26: 751-6 (2016) BindingDB Entry DOI: 10.7270/Q261124T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50143085 (CHEMBL3759846) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilization | Bioorg Med Chem Lett 26: 751-6 (2016) BindingDB Entry DOI: 10.7270/Q261124T | |||||||||||
More data for this Ligand-Target Pair |