BDBM50143098 6-(4-Methoxy-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine::CHEMBL300867

SMILES: COc1ccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)cc1

InChI Key: InChIKey=AAZYXOJZFFSUBA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143098 (6-(4-Methoxy-benzyloxy)-3-phenyl-[1,2,4]triazolo[3...) Show SMILES COc1ccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C23H18N4O2/c1-28-18-13-11-16(12-14-18)15-29-23-20-10-6-5-9-19(20)22-25-24-21(27(22)26-23)17-7-3-2-4-8-17/h2-14H,15H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143098 (6-(4-Methoxy-benzyloxy)-3-phenyl-[1,2,4]triazolo[3...) Show SMILES COc1ccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C23H18N4O2/c1-28-18-13-11-16(12-14-18)15-29-23-20-10-6-5-9-19(20)22-25-24-21(27(22)26-23)17-7-3-2-4-8-17/h2-14H,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha3-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143098 (6-(4-Methoxy-benzyloxy)-3-phenyl-[1,2,4]triazolo[3...) Show SMILES COc1ccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C23H18N4O2/c1-28-18-13-11-16(12-14-18)15-29-23-20-10-6-5-9-19(20)22-25-24-21(27(22)26-23)17-7-3-2-4-8-17/h2-14H,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143098 (6-(4-Methoxy-benzyloxy)-3-phenyl-[1,2,4]triazolo[3...) Show SMILES COc1ccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C23H18N4O2/c1-28-18-13-11-16(12-14-18)15-29-23-20-10-6-5-9-19(20)22-25-24-21(27(22)26-23)17-7-3-2-4-8-17/h2-14H,15H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair