BDBM50143116 6-(3-Chloro-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine::CHEMBL301104

SMILES: Clc1cccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)c1

InChI Key: InChIKey=GXLMDLJKUOQUDD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143116 (6-(3-Chloro-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,...) Show SMILES Clc1cccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)c1 Show InChI InChI=1S/C22H15ClN4O/c23-17-10-6-7-15(13-17)14-28-22-19-12-5-4-11-18(19)21-25-24-20(27(21)26-22)16-8-2-1-3-9-16/h1-13H,14H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143116 (6-(3-Chloro-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,...) Show SMILES Clc1cccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)c1 Show InChI InChI=1S/C22H15ClN4O/c23-17-10-6-7-15(13-17)14-28-22-19-12-5-4-11-18(19)21-25-24-20(27(21)26-22)16-8-2-1-3-9-16/h1-13H,14H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143116 (6-(3-Chloro-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,...) Show SMILES Clc1cccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)c1 Show InChI InChI=1S/C22H15ClN4O/c23-17-10-6-7-15(13-17)14-28-22-19-12-5-4-11-18(19)21-25-24-20(27(21)26-22)16-8-2-1-3-9-16/h1-13H,14H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha3-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50143116 (6-(3-Chloro-benzyloxy)-3-phenyl-[1,2,4]triazolo[3,...) Show SMILES Clc1cccc(COc2nn3c(nnc3c3ccccc23)-c2ccccc2)c1 Show InChI InChI=1S/C22H15ClN4O/c23-17-10-6-7-15(13-17)14-28-22-19-12-5-4-11-18(19)21-25-24-20(27(21)26-22)16-8-2-1-3-9-16/h1-13H,14H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits in L(tk-) cells				J Med Chem 47: 1807-22 (2004) Article DOI: 10.1021/jm031020p BindingDB Entry DOI: 10.7270/Q2959H0R
					More data for this Ligand-Target Pair