BDBM50143217 CHEMBL3758362

SMILES: Cn1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)n1

InChI Key: InChIKey=KXAHIMXTQGQLOX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143217 (CHEMBL3758362) Show SMILES Cn1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)n1 Show InChI InChI=1S/C18H18N8O/c1-24-11-14(9-20-24)16-6-7-17(27)26(22-16)10-13-4-3-5-15(8-13)21-18-19-12-25(2)23-18/h3-9,11-12H,10H2,1-2H3,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair