BDBM50143218 CHEMBL3758187

SMILES: Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3nc4ccccc4[nH]3)c2)n1

InChI Key: InChIKey=VLBJTTAPCQKBLH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143218 (CHEMBL3758187) Show SMILES Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3nc4ccccc4[nH]3)c2)n1 Show InChI InChI=1S/C22H19N7O/c1-28-14-16(12-23-28)18-9-10-21(30)29(27-18)13-15-5-4-6-17(11-15)24-22-25-19-7-2-3-8-20(19)26-22/h2-12,14H,13H2,1H3,(H2,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair