BDBM50143250 CHEMBL3759611

SMILES: Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3ncc(cn3)-c3cnn(CCO)c3)c2)n1

InChI Key: InChIKey=DKMGJVAFZLFION-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143250 (CHEMBL3759611) Show SMILES Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3ncc(cn3)-c3cnn(CCO)c3)c2)n1 Show InChI InChI=1S/C24H23N9O2/c1-31-15-20(13-27-31)22-5-6-23(35)33(30-22)14-17-3-2-4-21(9-17)29-24-25-10-18(11-26-24)19-12-28-32(16-19)7-8-34/h2-6,9-13,15-16,34H,7-8,14H2,1H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair