BDBM50143261 CHEMBL3758926

SMILES: Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3ccc(C(O)=O)c(F)c3)c2)nc1

InChI Key: InChIKey=HRQDDDJWAOLLID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143261 (CHEMBL3758926) Show SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3ccc(C(O)=O)c(F)c3)c2)nc1 Show InChI InChI=1S/C26H20FN7O3/c1-33-15-19(13-30-33)18-11-28-26(29-12-18)31-20-4-2-3-16(9-20)14-34-24(35)8-7-23(32-34)17-5-6-21(25(36)37)22(27)10-17/h2-13,15H,14H2,1H3,(H,36,37)(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair