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BDBM50143300 (3aR,9bS)-1-Methyl-6-undecyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[2,3-f]quinolin-6-ium; iodide::(3aR,9bS)-1-methyl-6-undecyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[2,3-f]quinolin-6-ium iodide::CHEMBL441186

SMILES: CCCCCCCCCCC[n+]1cccc2[C@@H]3[C@@H](CCN3C)CCc12

InChI Key: InChIKey=NZJXQXBAIFQWPJ-OFNKIYASSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143300   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))		BDBM50143300
PNG
((3aR,9bS)-1-Methyl-6-undecyl-2,3,3a,4,5,9b-hexahyd...)
Show SMILES CCCCCCCCCCC[n+]1cccc2[C@@H]3[C@@H](CCN3C)CCc12
Show InChI InChI=1S/C23H39N2/c1-3-4-5-6-7-8-9-10-11-17-25-18-12-13-21-22(25)15-14-20-16-19-24(2)23(20)21/h12-13,18,20,23H,3-11,14-17,19H2,1-2H3/q+1/t20-,23+/m1/s1
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Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slices

Bioorg Med Chem Lett 14: 1869-74 (2004)


Article DOI: 10.1016/j.bmcl.2003.10.074
BindingDB Entry DOI: 10.7270/Q21N80JP
More data for this
Ligand-Target Pair