BDBM50144094 CHEMBL65613::[4-(5-Chloro-1H-indole-2-sulfonyl)-piperazin-1-yl]-[4-(imino-piperidin-1-yl-methyl)-phenyl]-methanone

SMILES: Clc1ccc2[nH]c(cc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCCC1

InChI Key: InChIKey=HZDFOLZBDXXSNA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144094 (CHEMBL65613 | [4-(5-Chloro-1H-indole-2-sulfonyl)-p...) Show SMILES Clc1ccc2[nH]c(cc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCCC1 Show InChI InChI=1S/C25H28ClN5O3S/c26-21-8-9-22-20(16-21)17-23(28-22)35(33,34)31-14-12-30(13-15-31)25(32)19-6-4-18(5-7-19)24(27)29-10-2-1-3-11-29/h4-9,16-17,27-28H,1-3,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair