BDBM50144110 4-[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazine-1-carbonyl]-N-methyl-benzamidine::CHEMBL65637

SMILES: CNC(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1

InChI Key: InChIKey=GQFNXDDBTWIRFN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144110 (4-[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazine-1...) Show SMILES CNC(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1 Show InChI InChI=1S/C23H23BrN4O3S/c1-26-22(25)16-2-4-17(5-3-16)23(29)27-10-12-28(13-11-27)32(30,31)21-9-7-18-14-20(24)8-6-19(18)15-21/h2-9,14-15H,10-13H2,1H3,(H2,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair