BDBM50144122 CHEMBL304859::[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-piperazin-1-yl]-[4-(imino-piperidin-1-yl-methyl)-phenyl]-methanone

SMILES: Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCCC1

InChI Key: InChIKey=JFDBIEOFTUQBLA-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144122 (CHEMBL304859 | [4-(6-Chloro-benzo[b]thiophene-2-su...) Show SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCCC1 Show InChI InChI=1S/C25H27ClN4O3S2/c26-21-9-8-20-16-23(34-22(20)17-21)35(32,33)30-14-12-29(13-15-30)25(31)19-6-4-18(5-7-19)24(27)28-10-2-1-3-11-28/h4-9,16-17,27H,1-3,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair