BDBM50144125 CHEMBL63690::[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazin-1-yl]-[4-(1-methyl-1,4,5,6-tetrahydro-pyrimidin-2-yl)-phenyl]-methanone

SMILES: CN1CCCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1

InChI Key: InChIKey=ZLQBASOJLFMBIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144125 (CHEMBL63690 | [4-(6-Bromo-naphthalene-2-sulfonyl)-...) Show SMILES CN1CCCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1 |c:5| Show InChI InChI=1S/C26H27BrN4O3S/c1-29-12-2-11-28-25(29)19-3-5-20(6-4-19)26(32)30-13-15-31(16-14-30)35(33,34)24-10-8-21-17-23(27)9-7-22(21)18-24/h3-10,17-18H,2,11-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair