BDBM50144131 4-[4-(5-Chloro-1H-indole-2-sulfonyl)-piperazine-1-carbonyl]-N-ethyl-N-methyl-benzamidine::CHEMBL65978

SMILES: CCN(C)C(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=OEFDHQAKZXNPIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144131 (4-[4-(5-Chloro-1H-indole-2-sulfonyl)-piperazine-1-...) Show SMILES CCN(C)C(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C23H26ClN5O3S/c1-3-27(2)22(25)16-4-6-17(7-5-16)23(30)28-10-12-29(13-11-28)33(31,32)21-15-18-14-19(24)8-9-20(18)26-21/h4-9,14-15,25-26H,3,10-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair