BDBM50144134 4-[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazine-1-carbonyl]-N,N-dimethyl-benzamidine::CHEMBL65877

SMILES: CN(C)C(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1

InChI Key: InChIKey=CTDMCLBHDKWVBZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144134 (4-[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazine-1...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Br)ccc2c1 Show InChI InChI=1S/C24H25BrN4O3S/c1-27(2)23(26)17-3-5-18(6-4-17)24(30)28-11-13-29(14-12-28)33(31,32)22-10-8-19-15-21(25)9-7-20(19)16-22/h3-10,15-16,26H,11-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair