BDBM50144135 1-(2-{4-(6-chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-benzoyl]-piperazin-2-yl}-acetyl)-piperidine-4-carboxylic acid::CHEMBL303345

SMILES: CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCC(CC1)C(O)=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1

InChI Key: InChIKey=YHXZONLQFOMVSY-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50144135 (1-(2-{4-(6-chloro-benzo[b]thiophene-2-sulfonyl)-1-...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCC(CC1)C(O)=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1 |c:4| Show InChI InChI=1S/C31H34ClN5O6S2/c1-34-13-10-33-29(34)20-2-4-21(5-3-20)30(39)37-15-14-36(45(42,43)28-16-23-6-7-24(32)17-26(23)44-28)19-25(37)18-27(38)35-11-8-22(9-12-35)31(40)41/h2-7,16-17,22,25H,8-15,18-19H2,1H3,(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50144135 (1-(2-{4-(6-chloro-benzo[b]thiophene-2-sulfonyl)-1-...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCC(CC1)C(O)=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1 |c:4| Show InChI InChI=1S/C31H34ClN5O6S2/c1-34-13-10-33-29(34)20-2-4-21(5-3-20)30(39)37-15-14-36(45(42,43)28-16-23-6-7-24(32)17-26(23)44-28)19-25(37)18-27(38)35-11-8-22(9-12-35)31(40)41/h2-7,16-17,22,25H,8-15,18-19H2,1H3,(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair