BDBM50144235 CHEMBL63750::N,N-Diethyl-4-{phenyl-[8-(3-phenyl-propyl)-8-aza-bicyclo[3.2.1]oct-3-ylidene]-methyl}-benzamide

SMILES: [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6]-c1ccccc1)\c1ccccc1

InChI Key: InChIKey=YMEAXELZMGDHIH-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50144235 (CHEMBL63750 | N,N-Diethyl-4-{phenyl-[8-(3-phenyl-p...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6]-c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C34H40N2O/c1-3-35(4-2)34(37)29-19-17-28(18-20-29)33(27-15-9-6-10-16-27)30-24-31-21-22-32(25-30)36(31)23-11-14-26-12-7-5-8-13-26/h5-10,12-13,15-20,31-32H,3-4,11,14,21-25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor				Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50144235 (CHEMBL63750 | N,N-Diethyl-4-{phenyl-[8-(3-phenyl-p...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6]-c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C34H40N2O/c1-3-35(4-2)34(37)29-19-17-28(18-20-29)33(27-15-9-6-10-16-27)30-24-31-21-22-32(25-30)36(31)23-11-14-26-12-7-5-8-13-26/h5-10,12-13,15-20,31-32H,3-4,11,14,21-25H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptor				Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50144235 (CHEMBL63750 | N,N-Diethyl-4-{phenyl-[8-(3-phenyl-p...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6]-c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C34H40N2O/c1-3-35(4-2)34(37)29-19-17-28(18-20-29)33(27-15-9-6-10-16-27)30-24-31-21-22-32(25-30)36(31)23-11-14-26-12-7-5-8-13-26/h5-10,12-13,15-20,31-32H,3-4,11,14,21-25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1				Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4
					More data for this Ligand-Target Pair