BDBM50144246 4-{[(1R,5S)-8-Allyl-8-aza-bicyclo[3.2.1]oct-(3E)-ylidene]-phenyl-methyl}-N,N-diethyl-benzamide::CHEMBL304989
SMILES: CCN(CC)C(=O)c1ccc(cc1)C(=C1/C[C@@H]2CC[C@H](C1)N2CC=C)\c1ccccc1
InChI Key: InChIKey=ZCAJUSLEHCCIDZ-XDGQVVELSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50144246 (4-{[(1R,5S)-8-Allyl-8-aza-bicyclo[3.2.1]oct-(3E)-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Binding affinity for delta opioid receptor | Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50144246 (4-{[(1R,5S)-8-Allyl-8-aza-bicyclo[3.2.1]oct-(3E)-y...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Binding affinity for mu opioid receptor | Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50144246 (4-{[(1R,5S)-8-Allyl-8-aza-bicyclo[3.2.1]oct-(3E)-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 177 | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Effective concentration against stimulation of [35S]-GTP-gammaS, binding in CHO cells transfected with the human opioid receptor delta 1 | Bioorg Med Chem Lett 14: 2109-12 (2004) Article DOI: 10.1016/j.bmcl.2004.02.051 BindingDB Entry DOI: 10.7270/Q25B01X4 | |||||||||||
More data for this Ligand-Target Pair |