BDBM50144531 4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-azetidine-1-carbonyl)-piperazine-1-carboxylic acid 1-isopropyl-2-methyl-propyl ester::CHEMBL72279

SMILES: CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C

InChI Key: InChIKey=LICYULLQPIZDET-MSOLQXFVSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50144531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against human tryptase was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against Thrombin was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Plasmin (Rattus norvegicus)	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against Plasmin was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	935	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against Trypsin was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against Urokinase-type plasminogen activator was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50144531 (4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...) Show SMILES CC(C)C(OC(=O)N1CCN(CC1)C(=O)N1[C@@H]([C@@H](CC2CCNCC2)C1=O)C(O)=O)C(C)C Show InChI InChI=1S/C23H38N4O6/c1-14(2)19(15(3)4)33-23(32)26-11-9-25(10-12-26)22(31)27-18(21(29)30)17(20(27)28)13-16-5-7-24-8-6-16/h14-19,24H,5-13H2,1-4H3,(H,29,30)/t17-,18+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against tissue type plasminogen activator was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair