BDBM50144602 CHEMBL3759127

SMILES: COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key: InChIKey=ODNMSCZTRWQCLL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50144602 (CHEMBL3759127) Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C30H34N6O3/c1-35-14-16-36(17-15-35)13-6-18-39-28-20-26-25(19-27(28)38-2)29(32-21-31-26)33-23-9-11-24(12-10-23)34-30(37)22-7-4-3-5-8-22/h3-5,7-12,19-21H,6,13-18H2,1-2H3,(H,34,37)(H,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human VEGFR-2 preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ...				Eur J Med Chem 109: 371-9 (2016) BindingDB Entry DOI: 10.7270/Q2M32XKS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50144602 (CHEMBL3759127) Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C30H34N6O3/c1-35-14-16-36(17-15-35)13-6-18-39-28-20-26-25(19-27(28)38-2)29(32-21-31-26)33-23-9-11-24(12-10-23)34-30(37)22-7-4-3-5-8-22/h3-5,7-12,19-21H,6,13-18H2,1-2H3,(H,34,37)(H,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...				Eur J Med Chem 109: 371-9 (2016) BindingDB Entry DOI: 10.7270/Q2M32XKS
					More data for this Ligand-Target Pair