BDBM50144735 CHEMBL75889::N-(4-Bromo-phenyl)-2-(5-chloro-2-methoxy-phenyl)-pyrimidine-4,6-diamine

SMILES: COc1ccc(Cl)cc1-c1nc(N)cc(Nc2ccc(Br)cc2)n1

InChI Key: InChIKey=PUSBQVLXBYVHHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50144735 (CHEMBL75889 | N-(4-Bromo-phenyl)-2-(5-chloro-2-met...) Show SMILES COc1ccc(Cl)cc1-c1nc(N)cc(Nc2ccc(Br)cc2)n1 Show InChI InChI=1S/C17H14BrClN4O/c1-24-14-7-4-11(19)8-13(14)17-22-15(20)9-16(23-17)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc Curated by ChEMBL					Assay Description Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes				Bioorg Med Chem Lett 14: 2303-8 (2004) Article DOI: 10.1016/j.bmcl.2004.01.104 BindingDB Entry DOI: 10.7270/Q2Q23ZPH
					More data for this Ligand-Target Pair