BDBM50144950 3'-deoxyadenosine::9-(beta-D-3'-Deoxyribofuranosyl)adenine::9-Cordyceposidoadenine::9H-Purine, 6-amino-9-(3-deoxy-beta-D-ribofuranosyl)-::CHEMBL305686::Cordycepine::cordycepin
SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)C[C@H]1O
InChI Key: InChIKey=OFEZSBMBBKLLBJ-BAJZRUMYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 7.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Affinity for the Adenosine A1 receptor in the absence of GTP (A1-GTP) by using [3H]DPCPX as radioligand | J Med Chem 38: 4000-6 (1995) BindingDB Entry DOI: 10.7270/Q2W37WZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ghent Curated by ChEMBL | Assay Description Affinity for adenosine A1 receptor was determined, in the absence of GTP in rat cortical membrane. | J Med Chem 40: 3765-72 (1997) Article DOI: 10.1021/jm970176k BindingDB Entry DOI: 10.7270/Q2RF5VP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ghent Curated by ChEMBL | Assay Description Affinity for adenosine A1 receptor was determined, in the absence of GTP in rat cortical membrane. | J Med Chem 40: 3765-72 (1997) Article DOI: 10.1021/jm970176k BindingDB Entry DOI: 10.7270/Q2RF5VP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligand | J Med Chem 38: 4000-6 (1995) BindingDB Entry DOI: 10.7270/Q2W37WZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus) | BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) | UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Isis Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition HCV NS5B-mediated RNA synthesis | J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3 | |||||||||||
More data for this Ligand-Target Pair |