null

SMILES: OCCNC(=O)[C@H]1CC[C@@H](CC1)c1nc(c[nH]1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=VKIXPTPAIVWSBW-JOCQHMNTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50145040 (4-[4-(3-Trifluoromethyl-phenyl)-1H-imidazol-2-yl]-...) Show SMILES OCCNC(=O)[C@H]1CC[C@@H](CC1)c1nc(c[nH]1)-c1cccc(c1)C(F)(F)F |r,wU:9.12,wD:6.5,(36.76,-5.11,;35.21,-5.1,;34.44,-6.44,;32.9,-6.44,;32.12,-7.78,;32.89,-9.1,;30.59,-7.77,;29.81,-6.44,;28.27,-6.44,;27.5,-7.77,;28.27,-9.1,;29.81,-9.1,;25.96,-7.78,;25,-6.58,;23.56,-7.12,;23.63,-8.63,;25.11,-9.05,;22.32,-6.22,;22.49,-4.69,;21.24,-3.78,;19.83,-4.41,;19.67,-5.94,;20.92,-6.85,;18.25,-6.56,;16.82,-7.18,;17.63,-5.14,;18.87,-7.98,)| Show InChI InChI=1S/C19H22F3N3O2/c20-19(21,22)15-3-1-2-14(10-15)16-11-24-17(25-16)12-4-6-13(7-5-12)18(27)23-8-9-26/h1-3,10-13,26H,4-9H2,(H,23,27)(H,24,25)/t12-,13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
TCG Lifesciences Ltd. Curated by ChEMBL					Assay Description Inhibition of human ERG				Eur J Med Chem 46: 618-30 (2011) Article DOI: 10.1016/j.ejmech.2010.11.042 BindingDB Entry DOI: 10.7270/Q2WQ052W
					More data for this Ligand-Target Pair