BDBM50145168 CHEMBL3764319
SMILES: CC(=O)N1CCc2cc(ccc12)S(=O)(=O)NNc1ccc(Br)cc1
InChI Key: InChIKey=NMVZDUVPPFKJME-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM50145168 (CHEMBL3764319) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 231 | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan | J Med Chem 59: 419-30 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM50145168 (CHEMBL3764319) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of human Indoleamine 2,3-dioxygenase using L-tryptophan as substrate by emission fluorescence analysis | J Med Chem 59: 419-30 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V69 | |||||||||||
More data for this Ligand-Target Pair |