BDBM50145224 2-(4-Dimethylaminomethyl-phenyl)-1H-benzoimidazole-4-carboxylic acid amide::CHEMBL81125
SMILES: CN(C)Cc1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O
InChI Key: InChIKey=XZBZQFNYQMZQTC-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM50145224 (2-(4-Dimethylaminomethyl-phenyl)-1H-benzoimidazole...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Newcastle Curated by ChEMBL | Assay Description Binding affinity towards human poly(ADP-ribose) polymerase-1 (PARP-1) | Bioorg Med Chem Lett 14: 2433-7 (2004) Article DOI: 10.1016/j.bmcl.2004.03.017 BindingDB Entry DOI: 10.7270/Q2542N1M | |||||||||||
More data for this Ligand-Target Pair |