BDBM50145256 1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-2-[2-((S)-methoxymethyl)-pyrrolidin-1-yl]-ethanone::CHEMBL81103

SMILES: COC[C@@H]1CCCN1CC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1

InChI Key: InChIKey=LRABQNQVQMNJAY-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50145256 (1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[...) Show SMILES COC[C@@H]1CCCN1CC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1 Show InChI InChI=1S/C26H35FN4O2S/c1-33-17-21-5-3-11-31(21)16-24(32)30-12-9-18(10-13-30)15-28-26-29-25-22-14-20(27)8-7-19(22)4-2-6-23(25)34-26/h7-8,14,18,21H,2-6,9-13,15-17H2,1H3,(H,28,29)/t21-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor				Bioorg Med Chem Lett 14: 2451-7 (2004) Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1
					More data for this Ligand-Target Pair